Application | Comment | Organism |
---|---|---|
medicine | construction of a immunotoxin consisting of the non-toxic type 2 ribosome-inactivating protein nigrin b linked to the monoclonal anti-human CD105 antibody 44G4. The immunotoxin kills specifically mouse fibroblasts expressing the biomarker CD105 with an IC50 value of 0.6 nM while nigrin does it at 0.24 microM. The immunotoxin accumulates in a perinuclear region | Sambucus nigra |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of a immunotoxin consisting of the non-toxic type 2 ribosome-inactivating protein nigrin b linked to the monoclonal anti-human CD105 antibody 44G4. The immunotoxin kills specifically mouse fibroblasts expressing the biomarker CD105 with an IC50 value of 0.6 nM while nigrin does it at 0.24 microM | Sambucus nigra |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sambucus nigra | - |
isoform nigrin B | - |