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Literature summary for 3.2.2.22 extracted from

  • Yan, L.; Wu, S.; Li, H.G.; Li, J.H.; Wong, R.N.S.; Shi, Q.L.; Dong, Y.C.
    Role of TYR70 in the N-glycosidase activity of neo-trichosanthin (1999), Toxicon, 37, 961-972.
    View publication on PubMed
Search for more literature for 3.2.2.22

Application

Application Comment Organism
medicine TCS used as abortifacient in China Trichosanthes sp.

Cloned(Commentary)

Cloned (Comment) Organism
-
 Trichosanthes sp.

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structures of several E85 mutant TCS complexes with adenosine-5'-monophosphate, E85A, space group P2(1)2(1)2(1), unit cell constants a = 38.3, b = 76.7, c= 79.2 Trichosanthes sp.
crystals of n-TCS, space group P2(1)2(1)2(1), unit cell constants a = 3.839 nm, b = 7.652 nm, c = 7.963 nm and mutant Y70A, space group P2(1)2(1)2(1), a = 3.830, b = 7.646, c = 7.943 Trichosanthes sp.
E85Q, space group P2(1)2(1)2(1), unit cell constants a = 38.0, b = 75.9, c= 78.4 Trichosanthes sp.

Protein Variants

Protein Variants Comment Organism
Y70A n-TCS mutant Trichosanthes sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
rRNA + H2O Trichosanthes sp.
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Trichosanthes sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
rRNA + H2O
-
 Trichosanthes sp. ?
-
 ?

Synonyms

Synonyms Comment Organism
n-TCS
-
 Trichosanthes sp.
neo-trichosanthin
-
 Trichosanthes sp.
TCS
-
 Trichosanthes sp.