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Literature summary for 3.2.2.21 extracted from

  • Alseth, I.; Rognes, T.; Lindback, T.; Solberg, I.; Robertsen, K.; Kristiansen, K.I.; Mainieri, D.; Lillehagen, L.; Kolsto, A.B.; Bjoras, M.
    A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD (2006), Mol. Microbiol., 59, 1602-1609.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.2.21

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21, AlkD Bacillus cereus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
25000
-
 x * 25000, AlkD, SDS-PAGE Bacillus cereus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bacillus cereus AlkD is involved exclusively in the repair of alkylation damage ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bacillus cereus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bacillus cereus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alkylated DNA + H2O AlkD has high activity towards 7-methylguanine but removes 3-methylguanine more slowly as compared with Escherichia coli AlkA Bacillus cereus 3-methyladenine + 7-methylguanine + 3-methylguanine
-
 ?
additional information AlkD is involved exclusively in the repair of alkylation damage Bacillus cereus ?
-
 ?
additional information no detectable affinity for hypoxanthine, 1,N6-ethenoadenine, 8-oxoguanine and 5-formyluracil Bacillus cereus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 25000, AlkD, SDS-PAGE Bacillus cereus

Synonyms

Synonyms Comment Organism
AlkD
-
 Bacillus cereus