Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma vivax | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
IAG-NH | - |
Trypanosoma vivax |
purine-specific inosine-adenosine-guanosine nucleoside hydrolase | - |
Trypanosoma vivax |
purine-specific nucleoside hydrolase | - |
Trypanosoma vivax |
General Information | Comment | Organism |
---|---|---|
additional information | regulation mechanisms of key residues and loops 1 and 2 for the base release, molecular dynamics simulations, overview. The base release process is not the rate-limiting step in the entire hydrolysis process, and the very low barrier of about 5.6 kcal/mol can bewashed out easily by the notable exothermicity fromthe substrate hydrolysis step. Glu82/Trp83 in loop 1 and His247/Arg252 in loop 2 are important to modulate the base release. Partial helix-to-coil change of loop 2 occurs along with the base release process | Trypanosoma vivax |