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Literature summary for 3.2.1.28 extracted from

  • Garre, E.; Matallana, E.
    The three trehalases Nth1p, Nth2p and Ath1p participate in the mobilization of intracellular trehalose required for recovery from saline stress in Saccharomyces cerevisiae (2009), Microbiology, 155, 3092-3099.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
genes NTH1 and ATH1 Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
additional information construction of mutants defective in neutral trehalase and/or acid trehalase isozymes, metabolism phenotypes and viability, overview. The mutants show altered recovery from salt stress compared to the wild-type enzyme Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
trehalose + H2O Saccharomyces cerevisiae
-
2 D-glucose
-
?
trehalose + H2O Saccharomyces cerevisiae MCY1264
-
2 D-glucose
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
neutral trehalase and acid trehalase isozymes encoded by the NTH1 and ATH1 genes
-
Saccharomyces cerevisiae MCY1264
-
neutral trehalase and acid trehalase isozymes encoded by the NTH1 and ATH1 genes
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trehalose + H2O
-
Saccharomyces cerevisiae 2 D-glucose
-
?
trehalose + H2O
-
Saccharomyces cerevisiae MCY1264 2 D-glucose
-
?

Synonyms

Synonyms Comment Organism
acid trehalase
-
Saccharomyces cerevisiae
neutral trehalase
-
Saccharomyces cerevisiae

General Information

General Information Comment Organism
physiological function role for Nth2p in the mobilization of intracellular trehalose during salt-stress recovery, overview Saccharomyces cerevisiae