Any feedback?
Literature summary for 3.2.1.28 extracted from
- Absorption of toxic beta-glucosides produced by plants and their effects on tissue trehalase from insects (2006), Comp. Biochem. Physiol. B, 143, 367-373.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| amygdalin | induces the enzyme in different organs, e.g. Malphigian tubules, midgut, fat body, hemolymph, and body wall, when feeded to larvae | Spodoptera frugiperda |  |
| esculin | induces the enzyme in different organs, e.g. Malphigian tubules, midgut, fat body, hemolymph, and body wall, when feeded to larvae | Spodoptera frugiperda | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| amygdalin | - |
Diatraea saccharalis | |
| amygdalin | - |
Musca domestica | |
| amygdalin | - |
Spodoptera frugiperda | |
| amygdalin | - |
Tenebrio molitor | |
| esculin | - |
Spodoptera frugiperda | |
| esculin | - |
Tenebrio molitor | |
| mandelonitrile | - |
Diatraea saccharalis | |
| mandelonitrile | - |
Musca domestica | |
| mandelonitrile | - |
Spodoptera frugiperda | |
| mandelonitrile | - |
Tenebrio molitor | |
| additional information | inhibitory potency of plant-derived inhibitors in different tissues on soluble and membranous enzymes, overview, mechanism of insect tocircumvent trehalase inhibition caused by glucosides, overview | Diatraea saccharalis | |
| additional information | inhibitory potency of plant-derived inhibitors in different tissues on soluble and membranous enzymes, overview, mechanism of insect tocircumvent trehalase inhibition caused by glucosides, overview | Musca domestica | |
| additional information | inhibitory potency of plant-derived inhibitors in different tissues on soluble and membranous enzymes, overview, mechanism of insect tocircumvent trehalase inhibition caused by glucosides, overview | Spodoptera frugiperda | |
| additional information | inhibitory potency of plant-derived inhibitors in different tissues on soluble and membranous enzymes, overview, mechanism of insect tocircumvent trehalase inhibition caused by glucosides, overview | Tenebrio molitor | |
| phlorizin | - |
Diatraea saccharalis | |
| phlorizin | - |
Musca domestica | |
| phlorizin | - |
Spodoptera frugiperda | |
| phlorizin | - |
Tenebrio molitor | |
| prunasin | - |
Diatraea saccharalis | |
| prunasin | - |
Musca domestica | |
| prunasin | - |
Spodoptera frugiperda | |
| prunasin | - |
Tenebrio molitor | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Tenebrio molitor | 16020 | - |
| membrane | - |
Spodoptera frugiperda | 16020 | - |
| membrane | - |
Musca domestica | 16020 | - |
| membrane | - |
Diatraea saccharalis | 16020 | - |
| soluble | - |
Tenebrio molitor | - |
- |
| soluble | - |
Spodoptera frugiperda | - |
- |
| soluble | - |
Musca domestica | - |
- |
| soluble | - |
Diatraea saccharalis | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha,alpha-trehalose + H2O | Tenebrio molitor | the enzyme is important in insect metabolism with trehalose being the main circulating sugar in the organism with functions in storage, fuel for flight, and as a cryoprotector, in hemolymph trehalose is important for carbohydrate intake and nutritional homeostasis, enzyme deficiency leads to severe metabolic problems | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | Spodoptera frugiperda | the enzyme is important in insect metabolism with trehalose being the main circulating sugar in the organism with functions in storage, fuel for flight, and as a cryoprotector, in hemolymph trehalose is important for carbohydrate intake and nutritional homeostasis, enzyme deficiency leads to severe metabolic problems | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | Musca domestica | the enzyme is important in insect metabolism with trehalose being the main circulating sugar in the organism with functions in storage, fuel for flight, and as a cryoprotector, in hemolymph trehalose is important for carbohydrate intake and nutritional homeostasis, enzyme deficiency leads to severe metabolic problems | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | Diatraea saccharalis | the enzyme is important in insect metabolism with trehalose being the main circulating sugar in the organism with functions in storage, fuel for flight, and as a cryoprotector, in hemolymph trehalose is important for carbohydrate intake and nutritional homeostasis, enzyme deficiency leads to severe metabolic problems | 2 D-glucose | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Diatraea saccharalis | - |
- |
- |
| Musca domestica | - |
- |
- |
| Spodoptera frugiperda | - |
- |
- |
| Tenebrio molitor | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| body wall | larval | Tenebrio molitor | - |
| body wall | larval | Spodoptera frugiperda | - |
| body wall | larval | Musca domestica | - |
| body wall | larval | Diatraea saccharalis | - |
| fat body | larval | Tenebrio molitor | - |
| fat body | larval | Spodoptera frugiperda | - |
| fat body | larval | Musca domestica | - |
| hemolymph | larval | Tenebrio molitor | - |
| hemolymph | larval | Spodoptera frugiperda | - |
| hemolymph | larval | Musca domestica | - |
| hemolymph | larval, only soluble | Diatraea saccharalis | - |
| larva | - |
Tenebrio molitor | - |
| larva | - |
Spodoptera frugiperda | - |
| larva | - |
Musca domestica | - |
| larva | - |
Diatraea saccharalis | - |
| malpighian tubule | larval | Tenebrio molitor | - |
| malpighian tubule | larval | Spodoptera frugiperda | - |
| malpighian tubule | larval | Musca domestica | - |
| malpighian tubule | larval | Diatraea saccharalis | - |
| midgut | larval | Spodoptera frugiperda | - |
| midgut | larval | Musca domestica | - |
| midgut | larval | Diatraea saccharalis | - |
| midgut | over 60% of total enzyme activity, larval | Tenebrio molitor | - |
| additional information | distribution in the soluble and membrane fractions of the tissues, overview | Tenebrio molitor | - |
| additional information | distribution in the soluble and membrane fractions of the tissues, overview | Spodoptera frugiperda | - |
| additional information | distribution in the soluble and membrane fractions of the tissues, overview | Musca domestica | - |
| additional information | no activity in the fat body, distribution in the soluble and membrane fractions of the tissues, overview | Diatraea saccharalis | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| alpha,alpha-trehalose + H2O | - |
Tenebrio molitor | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | - |
Spodoptera frugiperda | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | - |
Musca domestica | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | - |
Diatraea saccharalis | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | the enzyme is important in insect metabolism with trehalose being the main circulating sugar in the organism with functions in storage, fuel for flight, and as a cryoprotector, in hemolymph trehalose is important for carbohydrate intake and nutritional homeostasis, enzyme deficiency leads to severe metabolic problems | Tenebrio molitor | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | the enzyme is important in insect metabolism with trehalose being the main circulating sugar in the organism with functions in storage, fuel for flight, and as a cryoprotector, in hemolymph trehalose is important for carbohydrate intake and nutritional homeostasis, enzyme deficiency leads to severe metabolic problems | Spodoptera frugiperda | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | the enzyme is important in insect metabolism with trehalose being the main circulating sugar in the organism with functions in storage, fuel for flight, and as a cryoprotector, in hemolymph trehalose is important for carbohydrate intake and nutritional homeostasis, enzyme deficiency leads to severe metabolic problems | Musca domestica | 2 D-glucose | - |
? | |
| alpha,alpha-trehalose + H2O | the enzyme is important in insect metabolism with trehalose being the main circulating sugar in the organism with functions in storage, fuel for flight, and as a cryoprotector, in hemolymph trehalose is important for carbohydrate intake and nutritional homeostasis, enzyme deficiency leads to severe metabolic problems | Diatraea saccharalis | 2 D-glucose | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glucose alpha-1,1-glucose hydrolase | - |
Tenebrio molitor |
| glucose alpha-1,1-glucose hydrolase | - |
Spodoptera frugiperda |
| glucose alpha-1,1-glucose hydrolase | - |
Musca domestica |
| glucose alpha-1,1-glucose hydrolase | - |
Diatraea saccharalis |
| trehalase | - |
Tenebrio molitor |
| trehalase | - |
Spodoptera frugiperda |
| trehalase | - |
Musca domestica |
| trehalase | - |
Diatraea saccharalis |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Tenebrio molitor |
| 30 | - |
assay at | Spodoptera frugiperda |
| 30 | - |
assay at | Musca domestica |
| 30 | - |
assay at | Diatraea saccharalis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
assay at | Tenebrio molitor |
| 6 | - |
assay at | Spodoptera frugiperda |
| 6 | - |
assay at | Musca domestica |
| 6 | - |
assay at | Diatraea saccharalis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
