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Literature summary for 3.2.1.24 extracted from

  • Kashyap, V.; Sharma, S.; Singh, V.; Sharma, S.K.; Saquib, M.; Srivastava, R.; Shaw, A.K.
    Deoxysugars as antituberculars and alpha-mannosidase inhibitors (2014), Antimicrob. Agents Chemother., 58, 3530-3532.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.24

Inhibitors

Inhibitors Comment Organism Structure
(6-butoxy-3-oxo-3,6-dihydro-2H-pyran-2-yl)methyl 2,2-dimethylpropanoate
-
 Mycobacterium tuberculosis
(6-methoxy-3-oxo-3,6-dihydro-2H-pyran-2-yl)methyl 2,2-dimethylpropanoate
-
 Mycobacterium tuberculosis
[6-(3-methylbutoxy)-3-oxo-3,6-dihydro-2H-pyran-2-yl]acetonitrile
-
 Mycobacterium tuberculosis
[6-(3-methylbutoxy)-3-oxo-3,6-dihydro-2H-pyran-2-yl]methyl 2,2-dimethylpropanoate
-
 Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-
Mycobacterium tuberculosis H37Rv
-
-
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.04244
-
 [6-(3-methylbutoxy)-3-oxo-3,6-dihydro-2H-pyran-2-yl]acetonitrile pH not specified in the publication, at 37°C Mycobacterium tuberculosis
0.068
-
 (6-methoxy-3-oxo-3,6-dihydro-2H-pyran-2-yl)methyl 2,2-dimethylpropanoate pH not specified in the publication, at 37°C Mycobacterium tuberculosis
0.27
-
 (6-butoxy-3-oxo-3,6-dihydro-2H-pyran-2-yl)methyl 2,2-dimethylpropanoate pH not specified in the publication, at 37°C Mycobacterium tuberculosis
0.3539
-
 [6-(3-methylbutoxy)-3-oxo-3,6-dihydro-2H-pyran-2-yl]methyl 2,2-dimethylpropanoate pH not specified in the publication, at 37°C Mycobacterium tuberculosis