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Literature summary for 3.1.7.2 extracted from
- In vitro degradation of guanosine 3,5-bis(diphosphate) [ppGpp] by the spoT gene product [ppGppase] from auxotrophic strains of Escherichia coli: effects of various antibiotics and drugs (1980), Arch. Microbiol., 124, 229-232.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| chlorotetracycline | - |
Escherichia coli |  |
| Levallorphan | - |
Escherichia coli | |
| tetracycline | - |
Escherichia coli | |
| Thiostrepton | - |
Escherichia coli | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | activation | Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ppGpp + H2O | Escherichia coli | - |
ppG + diphosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ppGpp + H2O | - |
Escherichia coli | ppG + diphosphate | - |
? | |
| ppGpp + H2O | i.e. guanosine-3',5'-bis(diphosphate) | Escherichia coli | ppG + diphosphate | i.e. guanosine 5'-diphosphate | ? | |
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