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Literature summary for 3.1.4.17 extracted from
- Determination of Ca2+/calmodulin-stimulated phosphodiesterase activity in intact cells (2005), Methods Mol. Biol., 307, 85-92.
Application
| Application | Comment | Organism |
|---|---|---|
| molecular biology | description of a technique used to estimate the extent of PDE1 activation in vivo by measuring in vitro the PDE activity. The technique can be used to measure Ca2+/CaM-stimulated PDE activity in cultured cells or tissues | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| aortic vascular smooth muscle cell | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
description of a technique used to estimate the extent of PDE1 activation in vivo by measuring in vitro the PDE activity | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3',5'-cGMP + H2O | the technique can be used to measure Ca2+/CaM-stimulated PDE activity in cultured cells or tissues | Rattus norvegicus | 5'-GMP | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ca2+/calmodulin-stimulated phosphodiesterase | - |
Rattus norvegicus |
| PDE1 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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