Literature summary for 3.1.3.7 extracted from

Miyamoto, R.; Sugiura, R.; Kamitani, S.; Yada, T.; Lu, Y.; Sio, S.O.; Asakura, M.; Matsuhisa, A.; Shuntoh, H.; Kuno, T.
Tol1, a fission yeast phosphomonoesterase, is an in vivo target of lithium, and its deletion leads to sulfite auxotrophy (2000), J. Bacteriol., 182, 3619-3625.

Search for more literature for 3.1.3.7

Activating Compound

Activating Compound	Comment	Organism	Structure
K+	-	Schizosaccharomyces pombe

Application

Application	Comment	Organism
medicine	enzyme as a potential target of lithium therapy	Schizosaccharomyces pombe

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli	Schizosaccharomyces pombe

Inhibitors

Inhibitors	Comment	Organism	Structure
Li+	-	Schizosaccharomyces pombe
Na+	-	Schizosaccharomyces pombe

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.077	-	inositol 1,4-bisphosphate	pH 7.8, 30°C	Schizosaccharomyces pombe

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required	Schizosaccharomyces pombe

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
40000	-	-	Schizosaccharomyces pombe

Organism

Organism	UniProt	Comment	Textmining
Schizosaccharomyces pombe	-	KP767, KP812, KP656, KP801, KP803	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant enzyme	Schizosaccharomyces pombe

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
adenosine 2',5'-bisphosphate + H2O	-	Schizosaccharomyces pombe	adenosine 5'-phosphate + phosphate	-	?
adenosine 3',5'-bisphosphate + H2O	-	Schizosaccharomyces pombe	adenosine 5'-phosphate + phosphate	-	?
inositol 1,3,4-trisphosphate + H2O	-	Schizosaccharomyces pombe	?	-	?
inositol 1,4-bisphosphate + H2O	-	Schizosaccharomyces pombe	inositol 4-phosphate + phosphate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)