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Literature summary for 3.1.3.53 extracted from

  • Payne, M.C.; Zhang, H.Y.; Shirasawa, Y.; Koga, Y.; Ikebe, M.; Benoit, J.N.; Fisher, S.A.
    Dynamic changes in expression of myosin phosphatase in a model of portal hypertension (2004), Am. J. Physiol., 286, H1801-H1810.
    View publication on PubMed

Application

Application Comment Organism
medicine in response to portal hypertension, abundance of MYPT 1 subunit is significantly reduced and switches to the leucine-zipper positive isoform Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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isoforms of enzyme targeting subunit 1, MYPT 1
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Source Tissue

Source Tissue Comment Organism Textmining
aorta and large capacitance vessels, predominantly expression of 3’-exon-out/leucine-zipper positive MYPT 1 isoform Rattus norvegicus
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artery first-order mesenteric resistance artery, high expression of enzyme with predominance of 3’-exon-excluded, leucine-zipper negative MYPT 1 isoform Rattus norvegicus
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artery pulmonary artery, predominantly expression of 3’-exon-out/leucine-zipper positive MYPT 1 isoform Rattus norvegicus
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vein mesenteric vein, high expression of enzyme with predominance of 3’-exon-excluded, leucine-zipper negative MYPT 1 isoform Rattus norvegicus
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