Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.3.5 extracted from

  • Johnson, S.M.
    The importance of B-cells and ecto-5'nucleotidase in Mycoplasma fermentans infection and the relevance to rheumatoid arthritis (2008), Immunology, 123, 187-196.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.5

Activating Compound

Activating Compound Comment Organism Structure
additional information infection with Mycoplasma fermentans strain M106 induces cellular ecto-5'-nucleotidase activity 8fold Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
adenosine 5'-(alpha,beta-methylene)diphosphate competitive inhibitor Homo sapiens
ADP competitive inhibitor Homo sapiens
ATP competitive inhibitor Homo sapiens
concanavalin A
-
 Homo sapiens
additional information not inhibited by beta-glycerophosphate Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0091
-
 AMP at pH 8.5 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000
-
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
B-lymphocyte
-
 Homo sapiens
-
CESS cell
-
 Homo sapiens
-
DAUDI cell
-
 Homo sapiens
-
RAJI cell
-
 Homo sapiens
-
serum
-
 Homo sapiens
-
synovial fluid
-
 Homo sapiens
-
THP-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-AMP + H2O
-
 Homo sapiens adenosine + phosphate
-
 ?

Subunits

Subunits Comment Organism
dimer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
CD73
-
 Homo sapiens
ecto-5'-nucleotidase
-
 Homo sapiens