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Literature summary for 3.1.3.5 extracted from

  • Bernardi, A.; Bavaresco, L.; Wink, M.R.; Jacques-Silva, M.C.; Delgado-Canedo, A.; Lenz, G.; Battastini, A.M.
    Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines (2007), Eur. J. Pharmacol., 569, 8-15.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
indomethacin 0.1 mM, causes 52% increase of activity in vivo after 48 h Rattus norvegicus
indomethacin 0.1 mM, causes 62% increase of activity in vivo after 48 h Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
C6 glioma cell
-
Rattus norvegicus
-
glioma cell line
-
Homo sapiens
-
glioma cell line
-
Rattus norvegicus
-
U-138MG cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-AMP + H2O
-
Homo sapiens adenosine + phosphate
-
?
5'-AMP + H2O
-
Rattus norvegicus adenosine + phosphate
-
?

Synonyms

Synonyms Comment Organism
ecto-5'-nucleotidase/CD73
-
Homo sapiens
ecto-5'-nucleotidase/CD73
-
Rattus norvegicus