Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ADP | strong, allosteric activiator | Columba livia |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
phosphate | - |
Columba livia |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.04 | - |
5'-dCMP | 37°C, pH 7.0, presence of 1 mM ADP | Columba livia | |
0.29 | - |
5'-AMP | 37°C, pH 7.0, presence of 1 mM ADP | Columba livia | |
0.75 | - |
5'-dCMP | 37°C, pH 7.0 | Columba livia | |
1.67 | - |
5'-IMP | 37°C, pH 7.0, presence of 1 mM ADP | Columba livia | |
1.85 | - |
5'-AMP | 37°C, pH 7.0 | Columba livia | |
2 | 3 | 5'-dAMP | 37°C, pH 7.0 | Columba livia | |
5.2 | - |
5'-dAMP | 37°C, pH 7.0, presence of 1 mM ADP | Columba livia | |
10.8 | - |
5'-IMP | 37°C, pH 7.0 | Columba livia |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Columba livia | 5829 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43000 | - |
x * 43000, SDS-PAGE | Columba livia |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Columba livia | - |
isoform cN-I | - |
Purification (Comment) | Organism |
---|---|
- |
Columba livia |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | breast muscle | Columba livia | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
4.33 | - |
37°C, pH 7.0 | Columba livia |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5'-AMP + H2O | absence of ADP, 60% loss of activity | Columba livia | adenosine + phosphate | - |
? | |
5'-dAMP + H2O | presence of ADP, 66% of the activity with 5-AMP | Columba livia | deoxyadenosine + phosphate | - |
? | |
5'-dCMP + H2O | presence of ADP, 16% of the activity with 5-AMP | Columba livia | deoxycytidine + phosphate | - |
? | |
5'-dIMP + H2O | presence of ADP, 38% of the activity with 5-AMP | Columba livia | deoxyinosine + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 43000, SDS-PAGE | Columba livia |