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Literature summary for 3.1.3.16 extracted from
- Protein phosphatase 2A regulates deoxycytidine kinase activity via Ser-74 dephosphorylation (2014), FEBS Lett., 588, 727-732.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| okadaic acid | - |
Homo sapiens |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | activates | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphoprotein + H2O | Homo sapiens | - |
protein + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| protein A Sepharose beads chromatography | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| CCRF-CEM cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phosphoprotein + H2O | - |
Homo sapiens | protein + phosphate | - |
? | |
| phosphorylated deoxycytidine kinase + H2O | protein phosphatase 2A negatively regulates deoxycytidine kinase activity via Ser-74 dephosphorylation | Homo sapiens | deoxycytidine kinase + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PP2A | - |
Homo sapiens |
| protein phosphatase 2A | - |
Homo sapiens |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.0000001 | - |
pH and temperature not specified in the publication | Homo sapiens | okadaic acid | |
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