Cloned (Comment) | Organism |
---|---|
PP1alpha N-terminally tagged with a monomeric variant of red fluorescent protein is expressed in MDCKII cells | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
H248K | catalytically inactive mutant of PP1alpha | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
I-2 protein | PP1-specific inhibitor | Mus musculus | |
additional information | Par-3 does not inhibit the enzymatic activity of PP1alpha | Mus musculus | |
okadaic acid | - |
Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38000 | - |
PP1alpha, tandem mass spectrometry | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryo | mouse E13 embryonic tissue | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
14-3-3epsilon phosphoprotein + H2O | - |
Mus musculus | 14-3-3epsilon protein + phosphate | - |
? | |
KRpTIRR + H2O | - |
Mus musculus | KRTIRR + phosphate | - |
? | |
phosphorylated angiomotin + H2O | - |
Mus musculus | angiomotin + phosphate | - |
? | |
phosphorylated atypical protein kinase C + H2O | - |
Mus musculus | atypical protein kinase C + phosphate | - |
? | |
phosphorylated DNA-protease K + H2O | - |
Mus musculus | DNA-protease K + phosphate | - |
? | |
phosphorylated Par-3 + H2O | predominantly the alpha-isoform of PP1 binds phosphorylated Par-3 and specifically dephosphorylates at Ser-144 and Ser-824 | Mus musculus | Par-3 + phosphate | - |
? | |
phosphorylated Par-6 + H2O | - |
Mus musculus | Par-6 + phosphate | - |
? | |
SSpSLESLQTAVAEVTLNGNIPFHRPR + H2O | - |
Mus musculus | SSSLESLQTAVAEVTLNGNIPFHRPR + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PP1 | - |
Mus musculus |
PP1alpha | isoform | Mus musculus |
protein phosphatase 1 | - |
Mus musculus |