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Literature summary for 3.1.3.16 extracted from

  • Li, Y.; Wei, H.; Hsieh, T.C.; Pallas, D.C.
    Cdc55p-mediated E4orf4 growth inhibition in Saccharomyces cerevisiae is mediated only in part via the catalytic subunit of protein phosphatase 2A (2008), J. Virol., 82, 3612-3623.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.16

Activating Compound

Activating Compound Comment Organism Structure
Ppm1p regulates the assembly of PP2A heterotrimers Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
T364A the mutant associates with Cdc55p at near-wild type level Saccharomyces cerevisiae
T364D the mutation disrupts PP2ABAC heterotrimer formation, the Pph21p mutant does not associate stably with Cdc55p Saccharomyces cerevisiae
Y367E the mutation disrupts PP2ABAC heterotrimer formation, the Pph21p mutant does not associate stably with Cdc55p Saccharomyces cerevisiae
Y367F the mutant associates with Cdc55p at near-wild type level Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 strains BY4741 and W303
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoprotein + H2O
-
 Saccharomyces cerevisiae protein + phosphate
-
 ?

Subunits

Subunits Comment Organism
heterotrimer the heterotrimeric PP2A holoenzyme PP2ABAC consists of a B subunit complexed with the PP2A structural (A) and catalytic (C) subunits Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
Cdc55p B subunit of PP2A Saccharomyces cerevisiae
PP2A
-
 Saccharomyces cerevisiae
PP2ABAC B subunit-containing heterotrimeric PP2A holoenzyme Saccharomyces cerevisiae
Pph21p/Pph22p C subunit of PP2A Saccharomyces cerevisiae
protein phosphatase 2A
-
 Saccharomyces cerevisiae
Tpd3p A subunit of PP2A Saccharomyces cerevisiae