Protein Variants | Comment | Organism |
---|---|---|
L309Q | the mutant enzyme cannot be methylated | Mus musculus |
L309Q | the mutant enzyme cannot be methylated | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha 4 protein | rapamycin has no effect on PP2A-C association with the inhibitor alpha 4 protein | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
45000 | - |
wild type PP2A-C, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | methylation at Leu309 | Mus musculus |
side-chain modification | methylation at Leu309 | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
Mono Q column chromatography | Mus musculus |
Mono Q column chromatography | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
1682-A cell | - |
Rattus norvegicus | - |
AML-12 cell | - |
Mus musculus | - |
GN5 cell | - |
Rattus norvegicus | - |
GP6 cell | - |
Rattus norvegicus | - |
liver | fetal and adult liver | Rattus norvegicus | - |
THC-252 cell | - |
Rattus norvegicus | - |
THC-H5D cell | - |
Rattus norvegicus | - |
WB-311 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
KRpTIRR + H2O | - |
Mus musculus | KRTIRR + phosphate | - |
? | |
KRpTIRR + H2O | - |
Rattus norvegicus | KRTIRR + phosphate | - |
? | |
myelin basic phosphoprotein + H2O | - |
Mus musculus | myelin basic protein + phosphate | - |
? | |
myelin basic phosphoprotein + H2O | - |
Rattus norvegicus | myelin basic protein + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alpha4/PP2A-C | alpha4 binds to PP2A-C independent of the A and B subunits | Mus musculus |
alpha4/PP2A-C | alpha4 binds to PP2A-C independent of the A and B subunits | Rattus norvegicus |
PP2A | - |
Mus musculus |
PP2A | - |
Rattus norvegicus |
PP2A-C | PP2A catalytic subunit | Mus musculus |
PP2A-C | PP2A catalytic subunit | Rattus norvegicus |
protein phosphatase 2A | - |
Mus musculus |
protein phosphatase 2A | - |
Rattus norvegicus |