Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | phosphatase activity is increased to up to 49-62% by 3 mM | Rattus norvegicus | |
dithiothreitol | phosphatase activity is increased to up to 49-62% by 0.3 mM | Rattus norvegicus | |
tris(2-carboxyethyl)-phosphine hydrochloride | phosphatase activity is increased to up to 49-62% by 0.3 mM | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | phosphatase activity is decreased by 5 mM | Rattus norvegicus | |
dithiothreitol | phosphatase activity is decreased by 5 mM | Rattus norvegicus | |
okadaic acid | 91% inhibition of the total phosphatase activity | Rattus norvegicus | |
Phenylarsine oxide | potent dithiothreitol-reversible inhibition of PP2A | Rattus norvegicus | |
tris(2-carboxyethyl)-phosphine hydrochloride | phosphatase activity is decreased by 5 mM | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32000 | - |
1 * 35000 + 1 * 32000, SDS-PAGE | Rattus norvegicus |
35000 | - |
1 * 35000 + 1 * 32000, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Bio-Gel P-6 gel filtration | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
cerebral cortex | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
KRpTIRR + H2O | - |
Rattus norvegicus | KRTIRR + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 1 * 35000 + 1 * 32000, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
PP2Ac | - |
Rattus norvegicus |
protein phosphatase 2A | - |
Rattus norvegicus |
serine/threonine phosphatase | - |
Rattus norvegicus |