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Literature summary for 3.1.3.16 extracted from

  • Hrabchak, C.; Henderson, H.; Varmuza, S.
    A testis specific isoform of endophilin B1, endophilin B1t, interacts specifically with protein phosphatase-1c gamma2 in mouse testis and is abnormally expressed in PP1c gamma null mice (2007), Biochemistry, 46, 4635-4644.
    View publication on PubMed
Search for more literature for 3.1.3.16

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae strain AH109 Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
endophilin B1t
-
 Mus musculus
neurabin I
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
there is no reliable method of separating native PP1c isoforms directly from testis without contamination Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoprotein + H2O
-
 Mus musculus protein + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
PP1cgamma
-
 Mus musculus
protein phosphatase-1c gamma2 isoform of protein phosphatase 1 Mus musculus
serine/threonine phosphatase
-
 Mus musculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000012
-
 at 37°C, in 50 mM Tris-HCl, pH 7.5, 1 mg/ml bovine serum albumin, 1 mM MnCl2, and 0.1% beta-mercaptoethanol Mus musculus neurabin I
0.0005
-
 at 37°C, in 50 mM Tris-HCl, pH 7.5, 1 mg/ml bovine serum albumin, 1 mM MnCl2, and 0.1% beta-mercaptoethanol Mus musculus endophilin B1t