Activating Compound | Comment | Organism | Structure |
---|---|---|---|
arachidonic acid | causes loss of heat shock protein interaction and increases Ppp5 activity, the effect of arachidonic acid on Ppp5 is increased by Rho kinase inhibitor Y27632, which is not affecting alone | Homo sapiens | |
HSP70 | heat shock protein, activation of Ppp5 by dissociation from Hsp70 | Homo sapiens | |
Hsp90 | heat shock protein, activation of Ppp5 by dissociation from Hsp90 | Homo sapiens | |
additional information | activation of Ppp involves translocation from the nucleus to the cytoplasm, activation mechanism, overview | Homo sapiens | |
nocodazole | causes loss of heat shock protein interaction and increases Ppp5 activity | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression of FLAG-tagged Ppp5 in HEK-293 cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | activation of Ppp involves translocation from the nucleus to the cytoplasm | Homo sapiens | 5737 | - |
nucleus | activation of Ppp involves translocation from the nucleus to the cytoplasm | Homo sapiens | 5634 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
130000 | - |
x * 45000-50000 + x * 130000, recombinant Ppp5, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | - |
Homo sapiens |
Purification (Comment) | Organism |
---|---|
recombinant FLAG-tagged and/or HA-tagged Ppp5 from HEK-293 cells | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
HeLa cell | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
Subunits | Comment | Organism |
---|---|---|
? | x * 45000-50000 + x * 130000, recombinant Ppp5, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
Ppp5 | - |
Homo sapiens |
protein phosphatase 5 | - |
Homo sapiens |