Activating Compound | Comment | Organism | Structure |
---|---|---|---|
arachidonic acid | - |
Solanum lycopersicum | |
linoleic acid | - |
Solanum lycopersicum | |
linolenic acid | - |
Solanum lycopersicum | |
oleic acid | - |
Solanum lycopersicum |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Rattus norvegicus |
expression in Escherichia coli | Solanum lycopersicum |
Protein Variants | Comment | Organism |
---|---|---|
additional information | removal of the TPR domain leads to a higher specific activity than wild-type enzyme at pH 7.5 but not at pH 5 | Solanum lycopersicum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
okadaic acid | IC50: 0.0081 mM | Solanum lycopersicum |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | the 55000 Da isoform | Solanum lycopersicum | 5737 | - |
endoplasmic reticulum | the 63000 Da isoform | Solanum lycopersicum | 5783 | - |
membrane | the 63000 Da isoform, integral membran protein | Solanum lycopersicum | 16020 | - |
nucleus | the 55000 Da isoform | Solanum lycopersicum | 5634 | - |
soluble | the 55000 Da isoform | Solanum lycopersicum | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | when p-nitrophenyl phosphate is used as substrate 10 mM MgCl2 increases the activity, when phosphocasein is used as substrate 10 mM MgCl2 reduces the activity by 50% | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
- |
Solanum lycopersicum |
63000 | - |
- |
Solanum lycopersicum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P53042 | - |
- |
Solanum lycopersicum | Q84K11 | tomato | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.033 | - |
at pH 7.5 with p-nitrophenyl phosphate as substrate | Solanum lycopersicum |
0.034 | - |
at pH 5 with p-nitrophenyl phosphate as substrate | Solanum lycopersicum |
0.064 | - |
at pH 5 with p-nitrophenyl phosphate as substrate | Rattus norvegicus |
0.081 | - |
at pH 7.5 with p-nitrophenyl phosphate as substrate | Rattus norvegicus |
0.245 | - |
DELTATPR at pH 7.5 with p-nitrophenyl phosphate as substrate | Solanum lycopersicum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
p-nitrophenyl phosphate + H2O | - |
Rattus norvegicus | 4-nitrophenol + phosphate | - |
? | |
p-nitrophenyl phosphate + H2O | - |
Solanum lycopersicum | 4-nitrophenol + phosphate | - |
? | |
phosphorylated casein + H2O | - |
Rattus norvegicus | casein + phosphate | - |
? | |
phosphorylated casein + H2O | - |
Solanum lycopersicum | casein + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LePP5 | - |
Solanum lycopersicum |
PP5 | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0081 | - |
IC50: 0.0081 mM | Solanum lycopersicum | okadaic acid |