Literature summary for 3.1.3.16 extracted from

Lindenthal, C.; Klinkert, M.Q.
Identification and biochemical characterisation of a protein phosphatase 5 homologue from Plasmodium falciparum (2002), Mol. Biochem. Parasitol., 120, 257-268.

Search for more literature for 3.1.3.16

Activating Compound

Activating Compound	Comment	Organism	Structure
arachidonic acid	-	Plasmodium falciparum
oleic acid	-	Plasmodium falciparum

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli M15	Plasmodium falciparum

Inhibitors

Inhibitors	Comment	Organism	Structure
okadaic acid	IC50: 4 nM	Plasmodium falciparum

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	at lower concentrations than in the nucleus	Plasmodium falciparum	5737	-
nucleus	-	Plasmodium falciparum	5634	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
80000	-	x * 80000, SDS-PAGE	Plasmodium falciparum

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Plasmodium falciparum

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
p-nitrophenyl phosphate + H2O	very low activity	Plasmodium falciparum	p-nitrophenol + phosphate	-	?

Subunits

Subunits	Comment	Organism
?	x * 80000, SDS-PAGE	Plasmodium falciparum

Synonyms

Synonyms	Comment	Organism
PfPP5	-	Plasmodium falciparum

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.000004	-	IC50: 4 nM	Plasmodium falciparum	okadaic acid

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Release 2023.1 (January 2023)