Literature summary for 3.1.3.16 extracted from

Swiatek, W.; Sugajska, E.; Lankiewicz, L.; Hemmings, B.A.; Zolnierowicz, S.
Biochemical characterization of recombinant subunits of type 2A protein phosphatase overexpressed in Pichia pastoris (2000), Eur. J. Biochem., 267, 5209-5216.

Search for more literature for 3.1.3.16

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression in Pichia pastoris KM71 and G115	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
Co2+	-	Homo sapiens
Ni2+	-	Homo sapiens
okadaic acid	IC50: 0.66 nM	Homo sapiens
okadaic acid	-	Oryctolagus cuniculus
Zn2+	-	Homo sapiens
Zn2+	-	Oryctolagus cuniculus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	-	Oryctolagus cuniculus
Co2+	-	Oryctolagus cuniculus
Mg2+	-	Oryctolagus cuniculus
Mn2+	-	Oryctolagus cuniculus
Ni2+	-	Oryctolagus cuniculus

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Oryctolagus cuniculus	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
side-chain modification	methylation at the last C-terminal Leu-residue	Homo sapiens

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens
-	Oryctolagus cuniculus

Source Tissue

Source Tissue	Comment	Organism	Textmining
muscle	skeletal	Oryctolagus cuniculus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.7	-	-	Homo sapiens

Storage Stability

Storage Stability	Organism
-80°C, at least one year	Oryctolagus cuniculus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.00000066	-	IC50: 0.66 nM	Homo sapiens	okadaic acid

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Release 2023.1 (January 2023)