Protein Variants | Comment | Organism |
---|---|---|
E69Q | mutation of E69Q results in a 500fold increase of muscle isozyme I0.5 versus Ca2+ | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
AMP | - |
Oryctolagus cuniculus | |
Ca2+ | Glu 69 is essential for the high sensitivity of muscle fructose-1,6-bisphosphatase inhibition by calcium ions | Oryctolagus cuniculus | |
D-fructose 2,6-bisphosphate | - |
Oryctolagus cuniculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0021 | - |
D-fructose 1,6-bisphosphate | native rabbit muscle FBPase | Oryctolagus cuniculus | |
0.0031 | - |
D-fructose 1,6-bisphosphate | mutant E69Q of rabbit muscle FBPase | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose 1,6-bisphosphate + H2O | - |
Oryctolagus cuniculus | D-fructose 6-phosphate + phosphate | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00023 | - |
D-fructose 2,6-bisphosphate | native rabbit muscle FBPase | Oryctolagus cuniculus | |
0.00035 | - |
D-fructose 2,6-bisphosphate | mutant E69Q of rabbit muscle FBPase | Oryctolagus cuniculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00016 | - |
native rabbit muscle FBPase | Oryctolagus cuniculus | AMP | |
0.00021 | - |
mutant E69Q of rabbit muscle FBPase | Oryctolagus cuniculus | AMP | |
0.00074 | - |
native rabbit muscle FBPase | Oryctolagus cuniculus | Ca2+ |