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Literature summary for 3.1.3.11 extracted from
- Fructose-1,6-bisphosphatase mediates cellular responses to DNA damage and aging in Saccharomyces cerevisiae (2006), Mutat. Res., 594, 135-147.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | enzyme deletion mutant, reduced sensitivity to alkylating agent methymethane sulfonate and reduced production of reactive oxygen species. Overexpression of enzyme increases sensitivity to methymethane sulfonate, shortens life span and increases induction of RNR2 gene | Saccharomyces cerevisiae |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Saccharomyces cerevisiae | enzyme influences the connection between DNA damage, aging and oxidative stress | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
up-regulated expression by low doses of methymethane sulfonate in growth medium | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | enzyme influences the connection between DNA damage, aging and oxidative stress | Saccharomyces cerevisiae | ? | - |
? | |
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