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Literature summary for 3.1.3.11 extracted from

  • Nimmo, H.G.; Tipton, K.F.
    The purification of fructose 1,6-diphosphatase from ox liver and its activation by ethylenediaminetetra-acetate (1975), Biochem. J., 145, 323-334.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.3.11

Activating Compound

Activating Compound Comment Organism Structure
8-hydroxyquinoline activates Bos taurus
citrate activates Bos taurus
EDTA activation Bos taurus
EDTA required at pH 7.2 but not at pH 9.5 Bos taurus
EGTA activates Bos taurus
His activation Bos taurus
imidazole activates Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
Zn2+
-
 Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35500
-
 4 * 35500, SDS-PAGE Bos taurus
143000
-
 gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
22.5
-
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose 1,6-diphosphate + H2O
-
 Bos taurus D-fructose 6-phosphate + phosphate
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 35500, SDS-PAGE Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
-
 Bos taurus

pH Range

pH Minimum pH Maximum Comment Organism
6.3 10 pH 6.3: about 30% of maximal activity, pH 10.0: about 45% of maximal activity Bos taurus