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Literature summary for 3.1.3.11 extracted from
- Mouse thymoma cell line expresses a gluconeogenic enzyme, fructose 1,6-bisphosphatase (1989), Biochem. Biophys. Res. Commun., 158, 929-935.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| AMP | 0.073 mM, 50% inhibition | Mus musculus |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 37500 | - |
x * 37500, SDS-PAGE | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-fructose 1,6-diphosphate + H2O | Mus musculus | gluconeogenic enzyme | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| thymus lymphoma cell line | only trace amounts of enzyme activity in normal thymus tissue | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-fructose 1,6-diphosphate + H2O | gluconeogenic enzyme | Mus musculus | ? | - |
? | |
| D-fructose 1,6-diphosphate + H2O | - |
Mus musculus | D-fructose 6-phosphate + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 37500, SDS-PAGE | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Mus musculus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 8.5 | pH 7.0: about 90% of maximal activity, pH 8.5: about 35% of maximal activity | Mus musculus |
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Release 2023.1 (January 2023)
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