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Literature summary for 3.1.3.1 extracted from

  • Reilly, G.C.; Radin, S.; Chen, A.T.; Ducheyne, P.
    Differential alkaline phosphatase responses of rat and human bone marrow derived mesenchymal stem cells to 45S5 bioactive glass (2007), Biomaterials, 28, 4091-4097.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
mesenchymal stem cell elevated levels of alkaline phosphatase activity when grown on 45S5 bioactive glass as compared to standard tissue culture plastic. Similarly, exposure to the dissolution products of 45S5 elevates alkaline phosphatase activity and other osteogenic markers in these cells Rattus norvegicus
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mesenchymal stem cell human mesenchymal stem cells produce markedly less alkaline phosphatase activity than rat mesenchymal stem cell, regardless of cell culture conditions. No difference in alkaline phosphatase activity between human MSCs grown on 45S5 bioactive glass or tissue culture plastic, in samples from five different orthopaedic patients, regardless of culture media composition Homo sapiens
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