Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-thujaplicin | i.e. 2-hydroxy-3-(1-methylethyl)-2,4,6-cycloheptatrien-1-one, slight inhibition | Escherichia coli | |
alpha-thujaplicin | i.e. 2-hydroxy-3-(1-methylethyl)-2,4,6-cycloheptatrien-1-one | Homo sapiens | |
beta-thujaplicin | i.e. 2-hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one, slight inhibition | Escherichia coli | |
beta-thujaplicin | i.e. 2-hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one | Homo sapiens | |
beta-thujaplicinol | i.e. 2,7-dihydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one | Escherichia coli | |
beta-thujaplicinol | i.e. 2,7-dihydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one | Homo sapiens | |
gamma-thujaplicin | i.e. 2-hydroxy-5-(1-methylethyl)-2,4,6-cycloheptatrien-1-one, slight inhibition | Escherichia coli | |
gamma-thujaplicin | i.e. 2-hydroxy-5-(1-methylethyl)-2,4,6-cycloheptatrien-1-one | Homo sapiens | |
manicol | i.e. 1,2,3,4-tetrahydro-2,7-dihydroxy-9-methyl-2-(1-methylethyl)-6H-benzocyclohepten-6-one | Escherichia coli | |
manicol | i.e. 1,2,3,4-tetrahydro-2,7-dihydroxy-9-methyl-2-(1-methylethyl)-6H-benzocyclohepten-6-one | Homo sapiens | |
additional information | selectivity of tropolone derivatives for RNase H, IC50 values, inhibition mechanism, overview | Escherichia coli | |
additional information | selectivity of tropolone derivatives for RNase H, IC50 values, inhibition mechanism, overview | Homo sapiens | |
nootkatin | i.e. 2-hydroxy-5-(3-methyl-2-butenyl)-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one, slight inhibition | Escherichia coli | |
nootkatin | i.e. 2-hydroxy-5-(3-methyl-2-butenyl)-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one | Homo sapiens | |
tropolone | i.e. 2-hydroxy-2,4,6-cycloheptatrien-1-one, slight inhibition | Escherichia coli | |
tropolone | i.e. 2-hydroxy-2,4,6-cycloheptatrien-1-one | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA-RNA hybrid + H2O | - |
Escherichia coli | ? | - |
? | |
DNA-RNA hybrid + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ribonuclease H | - |
Escherichia coli |
ribonuclease H | - |
Homo sapiens |
RNase H | - |
Escherichia coli |
RNase H | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Escherichia coli | |
additional information | - |
additional information | - |
Homo sapiens |