Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of an RNase III inactivation mutant DELTArnc from Staphylococcus aureus strain 8325-4. The DELTArnc strain shows reduced extracellular protein levels and is less pathogenic compared with its parent strain | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
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Staphylococcus aureus | - |
- |
- |
Staphylococcus aureus NCTC 8325 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
RNase III | - |
Staphylococcus aureus |
General Information | Comment | Organism |
---|---|---|
physiological function | Staphylococcus aureus ribonuclease III belongs to the enzyme family known to degrade double-stranded RNAs. RNase III can regulate the pathogenicity of Staphylococcus aureus by influencing the level of extracellular proteins via two different ways respectively at different growth phases. During the lag phase of the bacterial growth cycle RNase III can influence the extracellular protein secretion via regulating the expression of secY2, one component of accessory secretory (sec) pathway. After Staphylococcus aureus cells grow to exponential phase, RNase III can regulate the expression of extracellular proteins by affecting the level of RNAIII | Staphylococcus aureus |