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BRENDA support

Literature summary for 3.1.26.3 extracted from

  • Chen, T.S.; Lai, R.C.; Lee, M.M.; Choo, A.B.; Lee, C.N.; Lim, S.K.
    Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs (2010), Nucleic Acids Res., 38, 215-224.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
synthetic construct
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
premicro-RNA + H2O RNase III treatment causes a preferential loss of RNA in the 50- to 100-nt region. After RNase III treatment, the ratio of pre- to mature micro-RNA is reduced for micro-RNAs such as hsa-let-7b and hsa-let-7g, in both conditioned medium and mesenchymal stem cells due to a decrease in premicro-RNA level coupled with a concomitant increase in mature micro-RNA level synthetic construct mature micro-RNA
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Synonyms

Synonyms Comment Organism
RNase III
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synthetic construct