Any feedback?
Literature summary for 3.1.2.6 extracted from
- Characterization of the gene encoding glyoxalase II from Leishmania donovani: A potential target for anti-parasite drugs (2006), Biochem. J., 393, 227-234.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Leishmania donovani |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.039 | - |
mono-(lactoyl)trypanothione | pH 7.2, 25°C | Leishmania donovani |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 23000 | - |
2 * 32500, calculated, 2 * 23000, SDS-PAGE | Leishmania donovani |
| 32500 | - |
2 * 32500, calculated, 2 * 23000, SDS-PAGE | Leishmania donovani |
| 46000 | - |
SDS-PAGE of enzyme after cross-linking with glutaraldehyde | Leishmania donovani |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Leishmania donovani | Q5I5K8 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| lactoylglutathione + H2O | little activity with this substrate | Leishmania donovani | D-lactate + glutathione | - |
? | |
| mono-(lactoyl)trypanothione + H2O | - |
Leishmania donovani | D-lactate + trypanothione | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 32500, calculated, 2 * 23000, SDS-PAGE | Leishmania donovani |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Leishmania donovani | calculated | - |
6 |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
