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Literature summary for 3.1.2.6 extracted from

  • Singla-Pareek, S.L.; Reddy, M.K.; Sopory, S.K.
    Genetic engineering of the glyoxalase pathway in tobacco leads to enhanced salinity tolerance (2003), Proc. Natl. Acad. Sci. USA, 100, 14672-14677.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
DNA sequence determination and analysis, expression in Escherichia coli BL21(DE3) Oryza sativa

Protein Variants

Protein Variants Comment Organism
additional information enhanced glyoxalase I and II enzyme levels, not only of one of the enzymes, by transgenic overexpression of a Oryza sativa enzyme lead to enhanced salinity stress tolerance, but no further modification of the phenotype Nicotiana tabacum
additional information transgenic cotransfer of the gene in addition to the glyoxalase I gene to Nicotiana tabacum by Agrobacterium tumefaciens infection leads to overexpression of the enzymes and enhanced salt tolerance in the transgenic tobacco plants, no further modification of the tobacco phenotype Oryza sativa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-(2-hydroxyacyl)glutathione + H2O Oryza sativa
-
glutathione + a 2-hydroxycarboxylate anion
-
?
S-D-lactoylglutathione + H2O Nicotiana tabacum enzyme is involved in the detoxification of methylglyoxal glutathione + D-lactate
-
?

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum
-
-
-
Oryza sativa Q940L0 cv. IRBB10
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-(2-hydroxyacyl)glutathione + H2O
-
Oryza sativa glutathione + a 2-hydroxycarboxylate anion
-
?
S-D-lactoylglutathione + H2O
-
Nicotiana tabacum glutathione + D-lactate
-
?
S-D-lactoylglutathione + H2O enzyme is involved in the detoxification of methylglyoxal Nicotiana tabacum glutathione + D-lactate
-
?

Synonyms

Synonyms Comment Organism
acetoacetylglutathione hydrolase
-
Nicotiana tabacum
acetoacetylglutathione hydrolase
-
Oryza sativa
Germ cell specific protein
-
Nicotiana tabacum
Germ cell specific protein
-
Oryza sativa
GLO II
-
Nicotiana tabacum
GLO II
-
Oryza sativa
glyoxalase II
-
Nicotiana tabacum
glyoxalase II
-
Oryza sativa
hydrolase, acetoacetylglutathione
-
Nicotiana tabacum
hydrolase, acetoacetylglutathione
-
Oryza sativa
hydrolase, hydroxyacylglutathione
-
Nicotiana tabacum
hydrolase, hydroxyacylglutathione
-
Oryza sativa
Round spermatid protein RSP29
-
Nicotiana tabacum
Round spermatid protein RSP29
-
Oryza sativa
S-2-hydroxylacylglutathione hydrolase
-
Nicotiana tabacum
S-2-hydroxylacylglutathione hydrolase
-
Oryza sativa