Protein Variants | Comment | Organism |
---|---|---|
W199F | mid-point of unfolding transition curve is not very different from that of wild-type. Stability of the active site is slightly affected | Homo sapiens |
W57F | mid-point of unfolding transition curve is not very different from that of wild-type enzyme. Stability of the active site is slightly affected | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Guanidine-HCl | below 1 M, inactivation occurs without loss of the secondary structure | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Km-values of wild-type and mutant enzymes | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | essential for maintainance of native structure of the enzyme. Binding to the apoenzyme occurs during an essential step of refolding | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |