Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
linolenoyl-CoA + H2O | - |
Mus musculus | CoA + linolenoate | - |
? | |
myristoyl-CoA + H2O | - |
Mus musculus | CoA + myristate | - |
? | |
oleoyl-CoA + H2O | - |
Mus musculus | CoA + oleate | - |
? | |
palmitoyl-CoA + H2O | - |
Mus musculus | CoA + palmitate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACOT2 | - |
Mus musculus |
acyl-CoA thioesterase-2 | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.6 | - |
assay at | Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | Ad-Acot2 mice have higher free fatty acid utilization during the rest phase of the day but readily switch to carbohydrate oxidation at night. In isolated Ad-Acot2 liver mitochondria, phosphorylating O2 consumption is elevated with lipid but not non-lipid substrate. While the monolysocardiolipin pool in expanded in Ad-Acot2 liver mitochondria, total cardiolipin is unchanged | Mus musculus |
metabolism | Acot2 enhances mitochondrial fatty acid oxidation | Mus musculus |