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Literature summary for 3.1.2.2 extracted from

  • Mukherjee, J.J.; Jay, F.T.; Choy, P.C.
    Purification, characterization and modulation of a microsomal carboxylesterase in rat liver for the hydrolysis of acyl-CoA (1993), Biochem. J., 295, 81-86.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.2.2

Activating Compound

Activating Compound Comment Organism Structure
lysophosphatidylcholine
-
 Rattus norvegicus
lysophosphatidylethanolamine
-
 Rattus norvegicus
phosphatidylcholine
-
 Rattus norvegicus
phosphatidylethanolamine
-
 Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
cardiolipin
-
 Rattus norvegicus
lysophosphatidic acid
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.017
-
 hexadecanoyl-CoA
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
 x * 56000, SDS-PAGE Rattus norvegicus
64000
-
 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + H2O Rattus norvegicus
-
 CoA + palmitate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1
-
-
 Rattus norvegicus
66.7
-
-
 Rattus norvegicus

Storage Stability

Storage Stability Organism
-70°C in the presence of 20% glycerol over 1 month Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl acetate + H2O
-
 Rattus norvegicus 4-nitrophenol + acetate
-
 ?
acyl-CoA + H2O long-chain fatty-acyl-CoA Rattus norvegicus CoA + a carboxylate
-
 ?
hexadecanoyl-CoA + H2O best substrate Rattus norvegicus CoA + hexadecanoate
-
 ?
hexadecanoyl-CoA + H2O i.e. palmitoyl-CoA Rattus norvegicus CoA + hexadecanoate
-
 ?
octadecanoyl-CoA + H2O i.e. stearoyl-CoA Rattus norvegicus CoA + octadecanoate
-
 ?
oleoyl-CoA + H2O
-
 Rattus norvegicus CoA + oleate
-
 ?
palmitoyl-CoA + H2O
-
 Rattus norvegicus CoA + palmitate
-
 ?

Subunits

Subunits Comment Organism
? x * 56000, SDS-PAGE Rattus norvegicus