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Literature summary for 3.1.13.1 extracted from

  • Murakami, H.; Goto, D.B.; Toda, T.; Chen, E.S.; Grewal, S.I.; Martienssen, R.A.; Yanagida, M.
    Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function (2007), PLoS ONE, 2, e317.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Schizosaccharomyces pombe RNase activity of Dis3 is required for proper kinetochore formation and establishment of kinetochore-microtubule interactions. Dis3 is suggested to contribute to kinetochore formation through an involvement in heterochromatic silencing at both outer centromeric repeats and within the central core region ?
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Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe P37202
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information RNase activity of Dis3 is required for proper kinetochore formation and establishment of kinetochore-microtubule interactions. Dis3 is suggested to contribute to kinetochore formation through an involvement in heterochromatic silencing at both outer centromeric repeats and within the central core region Schizosaccharomyces pombe ?
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Synonyms

Synonyms Comment Organism
Dis3
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Schizosaccharomyces pombe