Literature summary for 3.1.1.8 extracted from

Jung, H.A.; Jung, Y.J.; Hyun, S.K.; Min, B.S.; Kim, D.W.; Jung, J.H.; Choi, J.S.
Selective cholinesterase inhibitory activities of a new monoterpene diglycoside and other constituents from Nelumbo nucifera stamens (2010), Biol. Pharm. Bull., 33, 267-272.

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Inhibitors

Inhibitors	Comment	Organism	Structure
(2,6,6-trimethylcyclohex-1-en-1-yl)methyl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside	-	Equus caballus
5'-O-Methyladenosine	-	Equus caballus
Cycloartenol	-	Equus caballus
p-hydroxybenzoic acid	-	Equus caballus
vanilloloside	-	Equus caballus

Organism

Organism	UniProt	Comment	Textmining
Equus caballus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
butyrylthiocholine chloride + H2O	-	Equus caballus	?	-	?

Synonyms

Synonyms	Comment	Organism
BChE	-	Equus caballus
butyrylcholinesterase	-	Equus caballus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8	-	assay at	Equus caballus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.01393	-	-	Equus caballus	Cycloartenol
0.062	-	-	Equus caballus	p-hydroxybenzoic acid
0.083	-	-	Equus caballus	(2,6,6-trimethylcyclohex-1-en-1-yl)methyl 6-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
0.1	-	value above 0.1	Equus caballus	5'-O-Methyladenosine
0.205	-	-	Equus caballus	vanilloloside

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Release 2023.1 (January 2023)