Literature summary for 3.1.1.5 extracted from

Shanado, Y.; Kometani, M.; Uchiyama, H.; Koizumi, S.; Teno, N.
Lysophospholipase I identified as a ghrelin deacylation enzyme in rat stomach (2004), Biochem. Biophys. Res. Commun., 325, 1487-1494.

Search for more literature for 3.1.1.5

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
DNA containing thymine glycol	inhibits activity with ghrelin and with palmitoyllysophosphatidylglycerol	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0065	-	ghrelin	-	Rattus norvegicus
0.22	-	palmitoyllysophosphatidylglycerol	-	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant	Rattus norvegicus

Source Tissue

Source Tissue	Comment	Organism	Textmining
stomach	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.5	-	activity with palmitoyllysophosphatidylglycerol	Rattus norvegicus
2.3	-	activity with ghrelin	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ghrelin + H2O	-	Rattus norvegicus	des-acyl ghrelin + n-octanoic acid	-	?
palmitoyllysophosphatidylglycerol + H2O	-	Rattus norvegicus	glycerophosphoglycerol + palmitic acid	-	?

Synonyms

Synonyms	Comment	Organism
lysophospholipase I	-	Rattus norvegicus
LysoPLA I	-	Rattus norvegicus

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Release 2023.1 (January 2023)