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Literature summary for 3.1.1.4 extracted from
- Effect of calcineurin inhibitors on myotoxic activity of crotoxin and Bothrops asper phospholipase A2 myotoxins in vivo and in vitro (2006), Comp. Biochem. Physiol. C, 143, 284-294.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Calcineurin | required for CTX myotoxic and neurotoxic activity, overview | Bothrops asper |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Bothrops asper | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Bothrops asper | CTX shows myotoxic and neurotoxic activity requiring calcineurin, overview | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bothrops asper | P20474 | precursor | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Bothrops asper | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | CTX shows myotoxic and neurotoxic activity requiring calcineurin, overview | Bothrops asper | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| crotoxin | - |
Bothrops asper |
| CTX | - |
Bothrops asper |
| More | the enzyme belongs to the group II phospholipases A2 | Bothrops asper |
| PLA2 | - |
Bothrops asper |
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