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Literature summary for 3.1.1.4 extracted from
- Interaction of phospholipase A2 and its zymogen with divalent metal ions (1974), Biochemistry, 13, 1439-1445.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ba2+ | competitive inhibition | Sus scrofa |  |
| p-bromophenacyl bromide | - |
Sus scrofa | |
| Sr2+ | competitive inhibition | Sus scrofa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ba2+ | prevents p-bromophenacyl bromide inactivation | Sus scrofa | |
| Ba2+ | diminishes susceptibility to trypsin attack | Sus scrofa | |
| Ca2+ | prevents p-bromophenacyl bromide inactivation | Sus scrofa | |
| Ca2+ | diminishes susceptibility to trypsin attack | Sus scrofa | |
| Ca2+ | only one Ca2+-binding site | Sus scrofa | |
| Sr2+ | diminishes susceptibility to trypsin attack and prevents p-bromophenacyl bromide inactivation | Sus scrofa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phospholipids + H2O | Sus scrofa | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pancreas | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| phospholipids + H2O | - |
Sus scrofa | ? | - |
? | |
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