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Literature summary for 3.1.1.4 extracted from

  • Romero, G.; Thompson, K.; Biltonen, R.L.
    The activation of porcine pancreatic phospholipase A2 by dipalmitoylphosphatidylcholine large unilamellar vesicles (1987), J. Biol. Chem., 262, 13476-13482.
    View publication on PubMed
Search for more literature for 3.1.1.4

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ PLA2-binding is Ca2+-independent, PLA2-activation requires Ca2+ Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphatidylcholine + H2O Sus scrofa
-
 lysophosphatidylcholine + a fatty acid
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-dipalmitoyl-phosphatidylcholine + H2O
-
 Sus scrofa 1-palmitoyl-glycerophosphorylcholine + palmitic acid
-
 ?
phosphatidylcholine + H2O
-
 Sus scrofa 1-acylglycerophosphocholine + fatty acid
-
 ?
phosphatidylcholine + H2O
-
 Sus scrofa lysophosphatidylcholine + a fatty acid
-
 ?

Subunits

Subunits Comment Organism
dimer only the dimer is catalytically active, no data concerning MW Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.42
-
 1,2-dipalmitoyl-phosphatidylcholine large unilamellar vesicles Sus scrofa