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Literature summary for 3.1.1.34 extracted from

  • Keiper, T.; Schneider, J.G.; Dugi, K.A.
    Novel site in lipoprotein lipase (LPL415-438) essential for substrate interaction and dimer stability (2001), J. Lipid Res., 42, 1180-1186.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in HEK 293 cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
2 * 55000, dissociation of the dimer into monomers leads to irreversible loss of activity Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
triacylglycerol + H2O Homo sapiens
-
diacylglycerol + a carboxylate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
adipocyte
-
Homo sapiens
-
macrophage
-
Homo sapiens
-
muscle
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.7
-
substrate tributyrin Homo sapiens
39.2
-
substrate triolein Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
triacylglycerol + H2O
-
Homo sapiens diacylglycerol + a carboxylate
-
?
tributyrin + H2O
-
Homo sapiens ?
-
?
triolein + H2O
-
Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
dimer 2 * 55000, dissociation of the dimer into monomers leads to irreversible loss of activity Homo sapiens

Synonyms

Synonyms Comment Organism
LPL
-
Homo sapiens