Application | Comment | Organism |
---|---|---|
synthesis | production of (2R,3S)-3-(4-methoxyphenyl)glycidic acid methyl ester, which is an intermediate in the synthesis of diltiazem. diltiazem hydrochloride is a coronary vasodilator and a calcium channel blocker | Serratia marcescens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Serratia marcescens | - |
Sr41 8000 | - |
Serratia marcescens Sr41 8000 | - |
Sr41 8000 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-(4-methoxyphenyl)glycidic acid methyl ester + H2O | - |
Serratia marcescens | (2R,3S)-3-(4-methoxyphenyl)glycidic acid methyl ester + (2S,3R)-3-(4-methoxyphenyl)glycidic acid + methanol | - |
? | |
3-(4-methoxyphenyl)glycidic acid methyl ester + H2O | - |
Serratia marcescens Sr41 8000 | (2R,3S)-3-(4-methoxyphenyl)glycidic acid methyl ester + (2S,3R)-3-(4-methoxyphenyl)glycidic acid + methanol | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
- |
Serratia marcescens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
- |
Serratia marcescens |