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Literature summary for 3.1.1.2 extracted from
- Investigation of the possible protective role of gallic acid on paraoxanase and arylesterase activities in livers of rats with acute alcohol intoxication (2013), Cell Biochem. Funct., 31, 208-213.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | ethanol consumption causes a significant decrease in liver paraoxonase activity. Gallic acid treatment partly restores this decreased paraoxonase activity. A gallic acid dose of 100 mg/kg shows highest restoring effect for paraoxonase activity. The activity of arylesterase is decreased in the ethanol group, but this decrease is not significant. Gallic acid treatment restores the loss of this activity due to ethanol exposure | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | ethanol consumption causes a decrease in liver arylesterase activity, which is not significant. Gallic acid treatment restores the loss of this activity due to ethanol exposure. Ethanol consumption causes a significant decrease in liver paraoxonase activity, gallic acid treatment partly restores this decreased paraoxonase activity | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
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