Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P27169 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phenyl acetate + H2O | - |
Homo sapiens | phenol + acetate | - |
? |
Subunits | Comment | Organism |
---|---|---|
oligomer | once purified, human PON1 is as a mixture of at least two oligomerization states. The absence of human phosphate binding protein favors homo-oligomerization of PON1 into different state(s) of higher molecular size | Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
additional information | - |
human PON1 exhibits intrinsically a remarkable thermal stability. The association of human phosphate binding protein, though it does not change the denaturation temperature, strongly contributes to slow the rate of irreversible denaturation | Homo sapiens |
60 | - |
complete loss of activity above | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Homo sapiens |