Protein Variants | Comment | Organism |
---|---|---|
F222Y | hydrolysis of phenyl acetate, but not of paraoxon | Homo sapiens |
H115W | no hydrolysis of phenyl acetate, but hydrolysis of paraoxon. Phenyl acetate can act as an inhibitor | Homo sapiens |
H115W/N133S | no hydrolysis of phenyl acetate, but hydrolysis of paraoxon | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
diisopropylfluorophosphate | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.61 | - |
phenyl acetate | pH 8.0, 25°C, wild-type enzyme | Homo sapiens | |
0.81 | - |
phenyl acetate | pH 8.0, 25°C, mutant enzyme F222Y | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P27169 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phenyl acetate + H2O | - |
Homo sapiens | phenol + acetate | - |
? | |
phenylacetate + H2O | - |
Homo sapiens | phenol + acetate | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.52 | - |
diisopropylfluorophosphate | pH 8.0, 25°C, wild-type enzyme, substrate phenyl acetate | Homo sapiens |