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Literature summary for 3.1.1.2 extracted from

  • La Du, B.N.; Adkins, S.; Kuo, C.L.; Lipsig, D.
    Studies on human serum paraoxonase/arylesterase (1993), Chem. Biol. Interact., 87, 25-34.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
1,2-dilauroyl-phosphatidylcholine stimulation Homo sapiens
dioleoyl phosphatidylcholine stimulation Homo sapiens
lecithin stimulation Homo sapiens
lysolecithin stimulation Homo sapiens
phosphatidylcholine purified A or B-type esterases are stimulated Homo sapiens
phosphatidylethanolamine stimulation Homo sapiens
phosphatidylglycerol stimulation Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
6-palmityl-ascorbic acid
-
Homo sapiens
phosphatidylserine
-
Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
NaCl B-type esterase has relatively higher paraoxonase activity and is stimulated to a greater degree by 1 M NaCl than the A allozyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood serum in serum, the esterase is tightly bound to the high density lipoproteins, particularly apo A-l Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phenyl acetate + H2O the enzyme exists in two genetically determined allozymic forms, and these A and B allozymes possess both paraoxonase and arylesterase activities. B-type esterase has relatively higher paraoxonase activity and is stimulated to a greater degree by 1 M NaCl than the A allozyme Homo sapiens phenol + acetate
-
?

Synonyms

Synonyms Comment Organism
paraoxonase/arylesterase
-
Homo sapiens