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Literature summary for 3.1.1.1 extracted from

  • Wheelock, C.E.; Eder, K.J.; Werner, I.; Huang, H.; Jones, P.D.; Brammell, B.F.; Elskus, A.A.; Hammock, B.D.
    Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos (2005), Aquat. Toxicol., 74, 172-192.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
diagnostics use of enzyme as a more sensitive biomarker for exposure to organophosphate than acetylcholinesterase. Enzyme is not suitable as a biomarker for pyrethroid exposure Oncorhynchus tshawytscha

Inhibitors

Inhibitors Comment Organism Structure
chlorpyrifos significant inhibition of 56% and 79% after exposure to 0.0012 and 0.0073 mg/l, resp. Oncorhynchus tshawytscha
additional information exposure to esfenvalerate has little effect on enzyme activity Oncorhynchus tshawytscha

Organism

Organism UniProt Comment Textmining
Oncorhynchus tshawytscha
-
juvenile, after exposure to chlorpyrifos or esfenvalerate
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Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Oncorhynchus tshawytscha
-